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Implication: Not for pediatric use

Insulin glargine versus sitagliptin in insulin-naive patients with type 2 diabetes mellitus uncontrolled on metformin (EASIE): a multicentre, randomised open-label trial [J]

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Studies using oral doses of 500 mg per day showed only modest, variable increases in plasma glutathione levels across subjects, with the melanin index reduction measurable only under controlled spectrophotometric conditions after four weeks of consistent supplementation [1]